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About Us
Targeted Protein degradation relies on the formation of an optimal ternary complex, a process that is currently unpredictable and often demands labour-intensive, trial-and-error experimentation.
We have developed a chemogenetic platform for in cellulo induced proximity that directly addresses this challenge by enabling more precise identification of targetable regions on proteins for PROTAC development.
We are also applying this tool to other induced proximity mechanisms to explore potential new therapeutic modalities.